Detalhe da pesquisa
1.
G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling.
Cell
; 184(3): 655-674.e27, 2021 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33497611
2.
Dual proteolytic pathways govern glycolysis and immune competence.
Cell
; 159(7): 1578-90, 2014 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25525876
3.
Apoptotic stress causes mtDNA release during senescence and drives the SASP.
Nature
; 622(7983): 627-636, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37821702
4.
NDP52 acts as a redox sensor in PINK1/Parkin-mediated mitophagy.
EMBO J
; 42(5): e111372, 2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36514953
5.
Oxidative stress-induced phosphorylation of JIP4 regulates lysosomal positioning in coordination with TRPML1 and ALG2.
EMBO J
; 41(22): e111476, 2022 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36394115
6.
Mitochondrial sodium/calcium exchanger (NCLX) regulates basal and starvation-induced autophagy through calcium signaling.
FASEB J
; 38(3): e23454, 2024 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38315457
7.
Author Correction: Apoptotic stress causes mtDNA release during senescence and drives the SASP.
Nature
; 625(7995): E15, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38168624
8.
The evolution of selective autophagy as a mechanism of oxidative stress response: The evolutionarily acquired ability of selective autophagy receptors to respond to oxidative stress is beneficial for human longevity.
Bioessays
; 45(11): e2300076, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37603398
9.
PI(5)P regulates autophagosome biogenesis.
Mol Cell
; 57(2): 219-34, 2015 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-25578879
10.
A Mammalian Target of Rapamycin-Perilipin 3 (mTORC1-Plin3) Pathway is essential to Activate Lipophagy and Protects Against Hepatosteatosis.
Hepatology
; 74(6): 3441-3459, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34233024
11.
Lipids, lysosomes and mitochondria: insights into Lewy body formation from rare monogenic disorders.
Acta Neuropathol
; 141(4): 511-526, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33515275
12.
Identification of novel Atg3-Atg8 inhibitors using virtual screening for autophagy modulation.
Bioorg Chem
; 114: 105092, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34147881
13.
Transcriptional block of AMPK-induced autophagy promotes glutamate excitotoxicity in nutrient-deprived SH-SY5Y neuroblastoma cells.
Cell Mol Life Sci
; 77(17): 3383-3399, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-31720741
14.
Mitochondria are required for pro-ageing features of the senescent phenotype.
EMBO J
; 35(7): 724-42, 2016 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26848154
15.
The crosstalk of NAD, ROS and autophagy in cellular health and ageing.
Biogerontology
; 21(3): 381-397, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32124104
16.
The mTORC1-autophagy pathway is a target for senescent cell elimination.
Biogerontology
; 20(3): 331-335, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30798505
17.
PCV2 replication promoted by oxidative stress is dependent on the regulation of autophagy on apoptosis.
Vet Res
; 50(1): 19, 2019 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30836990
18.
Complex inhibitory effects of nitric oxide on autophagy.
Mol Cell
; 43(1): 19-32, 2011 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-21726807
19.
Autophagy: 'Self-Eating' Your Way to Longevity.
Subcell Biochem
; 90: 25-47, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30779005
20.
mTORC1 and Nutrient Homeostasis: The Central Role of the Lysosome.
Int J Mol Sci
; 19(3)2018 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29534520